{"id":56935,"date":"2025-01-19T21:09:53","date_gmt":"2025-01-19T20:09:53","guid":{"rendered":"https:\/\/www.easly.nl\/biomarkers\/cortisol-speeksel\/"},"modified":"2025-01-26T21:22:57","modified_gmt":"2025-01-26T20:22:57","slug":"cortisol-saliva","status":"publish","type":"biomarkers","link":"https:\/\/www.easly.nl\/en\/biomarkers\/cortisol-saliva\/","title":{"rendered":"Cortisol (saliva)"},"content":{"rendered":"\t\t
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Cortisol Meaning<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tCortisol is a hormone produced in the adrenal glands. Cortisol is also called the\r\nstress hormone, because under the influence of stress it is released by the adrenal glands\r\nreleased into the blood and initiates all kinds of body processes that enable the body to\r\ncope with this stress.\r\nFor example, cortisol promotes the production of glucose (sugar) and the breakdown of proteins to provide the\r\nbody cells the energy and building materials they need. Cortisol is released by the adrenal glands\r\nreleased in a 24-hour rhythm, also called a circadian rhythm. This means that the\r\ncortisol level is highest in the morning and lowest at night. When determining cortisol in\r\nsaliva, it is therefore also important that it is a saliva sample from the morning.\r\nAbnormal values of cortisol can be caused by too much stress. Also\r\ncertain diseases can also cause abnormal values. In Cushing’s disease, too much\r\ncortisol is produced. In Addison’s disease, the opposite happens; the adrenal glands\r\nmake too little cortisol. This can lead to very dangerous situations the moment the\r\nbody is in a stressful situation (for example, an infection). Caution! Oral\r\ncontraceptives (the pill) can give increased levels of cortisol.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Cortisol (saliva) Value<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Cortisol in Saliva: Values and Interpretation<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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You can also find the cortisol values in saliva and their interpretation in tabular form below, so you can easily understand what the values say about your health.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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  • Normal:<\/strong>\r\n\r\nA cortisol level in saliva between 2.94 and 19.67 nmol\/L is considered normal. This\r\nindicates a healthy hormonal balance. The cortisol value varies depending on the time\r\nof the day at which it is measured.<\/li>\r\n
  • Low:<\/strong>\r\n\r\nWhen the cortisol level is below 2.8 nmol\/L, it is considered abnormal and too low. This may indicate impaired adrenal function or another hormonal abnormality. Values between 2.8 and 2.94 nmol\/L are considered \u201celevated,\u201d meaning the value is at the lower limit of normal. Further testing may be helpful.<\/li>\r\n
  • High:<\/strong>\r\n\r\nA cortisol value above 19.67 nmol\/L is considered \u201celevated,\u201d meaning it is at the upper limit of normal. Values between 19.67 and 20.7 nmol\/L indicate increased adrenal activity, but are still within normal. If the value exceeds 20.7 nmol\/L, it is considered abnormal and too high. This may indicate stress, an adrenal disorder or other underlying conditions. Further interpretation is needed in conjunction with other hormonal values.<\/li>\r\n
  • Invalid:<\/strong>\r\n\r\nA value of 0 nmol\/L is considered invalid, possibly due to an error in the test or insufficient saliva material. A new measurement is recommended.\r\nThe cortisol value in saliva is highly dependent on the time of measurement because the hormone follows a day-night rhythm and peaks in the morning.<\/li>\r\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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    Cortisol (saliva) Values and Interpretation (in table)<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    You can also find the cortisol values in saliva and their interpretation in tabular form below, so you can easily understand what the values say about your health.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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    Result<\/th>Unit<\/th>Value min-max<\/th>Age<\/th>Gender<\/th>Biomarker interpretation<\/th>\n<\/tr>\n<\/thead>\n
    Not normal<\/span><\/td>nmol\/L<\/td>0 - 2,8<\/td>18 - 100<\/td>Male & Female<\/td>The cortisol is outside the normal range and is too low. Cortisol levels depend on the time of measurement as they vary throughout the day.<\/td>\n<\/tr>\n
    Take care<\/span><\/td>nmol\/L<\/td>2,8 - 2,94<\/td>18 - 100<\/td>Male & Female<\/td>The cortisol is still within the normal range, but is on the low side.<\/td>\n<\/tr>\n
    Normal<\/span><\/td>nmol\/L<\/td>2,94 - 19,67<\/td>18 - 100<\/td>Male & Female<\/td>The cortisol is good.<\/td>\n<\/tr>\n
    Take care<\/span><\/td>nmol\/L<\/td>19,67 - 20,7<\/td>18 - 100<\/td>Male & Female<\/td>The cortisol is still within the normal range, but is on the high side.<\/td>\n<\/tr>\n
    Not normal<\/span><\/td>nmol\/L<\/td>20,7 - 100<\/td>18 - 100<\/td>Male & Female<\/td>The cortisol is outside the normal range and is too high. Cortisol levels depend on the time of measurement as they vary throughout the day<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

    Explore all about cortisol in saliva: find out what normal, too high or too low levels mean for your health.<\/p>\n","protected":false},"template":"","biomarkers_category":[1670],"class_list":["post-56935","biomarkers","type-biomarkers","status-publish","hentry","biomarkers_category-hormones"],"acf":[],"yoast_head":"\nCortisol (saliva): Meaning and value<\/title>\n<meta name=\"description\" content=\"Explore all about cortisol in saliva: find out what normal, too high or too low levels mean for your health.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.easly.nl\/en\/biomarkers\/cortisol-saliva\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cortisol (saliva): Meaning and value\" \/>\n<meta property=\"og:description\" content=\"Explore all about cortisol in 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